Articles of Interest – May

Abstracts Only

Social media support for parents and young people with food allergy – an analysis of Facebook content, Archives of Disease in Childhood

Nurse led Paediatric Food Allergy Testing: A cost effective way to improve patient care and experience, Archives of Disease in Childhood

A systematic review of epinephrine degradation with exposure to excessive heat or cold, Annals of Asthma, Allergy and Immunology

Case Study – Endurance exercise after orange ingestion anaphylaxis, Medical Journal of Dr D Y Patil University

Spacers versus nebulizers in treatment of acute asthma – a prospective randomized study in preschool children, Journal of Asthma

Allergies Are Associated with Increased Disease Activity in Multiple Sclerosis, Neurology

Antibiotic use during pregnancy and asthma in preschool children: the influence of confounding., Clinical and Experimental Allergy

Formula and breast feeding in infant food allergy: A population-based study, Journal of Paediatrics and Child Health Formula and breast feeding in infant food allergy: A population-based study, Journal of Paediatrics and Child Health

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Articles of Interest – April

Abstracts Only

Breastfeeding and asthma outcomes at the age of 6 years. The Generation R Study, Pediatric Allergy and Immunology

Alcohol Intake During Pregnancy and Offspring’s Atopic Eczema Risk, Alcoholism: Clinical & Experimental Research

Two patients with acute pancreatitis after undergoing oral food challenges, The Journal of Allergy and Clinical Immunology: In Practice

Allergic reactions to milk appear sooner than reactions to hen’s eggs: a retrospective study, Journal of Negative Results in Biomedicine

Anti-allergic effects and related active constituents of mung bean (Vignaradiatus Linn) sprouts

Full Articles

Asthma and Food Allergy in Children: Is There a Connection or Interaction? Frontiers in Pediatrics

Preconceptional exposure to oral contraceptive pills and the risk of wheeze, asthma and rhinitis in children, Allergology International

Usefulness of molecular diagnosis in egg allergic children

BSACI advises GPs on tackling chronic urticaria and angio-oedema, Guidelines in Practice

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March – Articles of Interest

Lots of reading last month, here is the some of the more interesting stuff.

Abstract Only

The economic effect and outcome of delaying oral food challenges, Annals of Asthma, Allergy and Immunology

The potential immunonutritional role of Parmigiano Reggiano cheese in children with food allergy, Progress In Nutrition

Endotypes of Pollen Food Syndrome in Children with Seasonal Allergic Rhinoconjunctivitis: a molecular classification, European Journal of Allergy and Clinical Immunology

Nonallergic Rhinitis : Diagnosis, Immunology and Allergy Clinics of North America

Immunological Characterization of Dutch Sesame Seed-Allergic Patients, International Archives of Allergy and Immunology

Natural history of Hymenoptera venom allergy in children not treated with immunotherapy, Annals of Allergy, Asthma and Immunology

The Influence of Inhaled Corticosteroids on Pubertal Growth and Final Height in asthmatic children, Pediatric Allergy and Immunology

Wraparound eyeglasses improve symptoms and quality of life in patients with seasonal allergic rhinoconjunctivitis, International Forum of Allergy and Rhinology

Development of a prediction model of severe reaction in boiled egg challenges, Allergology International

Full Articles

A holistic approach is needed for children with atopic eczema – NICE Quality Standard, Guidelines in Practice

Diagnosing and Treating Intolerance to Carbohydrates in Children, Nutrients

Multicentre Double-Blind Placebo-Controlled Food Challenge Study in Children Sensitised to Cashew Nut, PLOS One

Cloning and characterization of recombinant tropomyosin of giant freshwater shrimp M. rosenbergii to determine major allergens causing allergic reactions among shrimp-allergic children, Asian Pacific Journal of Allergy and Immunology

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February – Articles of Interest

Abstracts Only

Duration of total and exclusive breastfeeding, timing of solid food introduction and risk of allergic diseases: a systematic review and meta-analysis, Thorax

The pathogenesis of rheumatoid arthritis is associated with milk or egg allergy, North American Journal of Medical Sciences

Mothers of children with food allergy: A discourse analysis of occupational identities, Journal of Occupational Science

Two non-specific lipid transfer proteins (nsLTP) from tomato seeds are associated to severe symptoms of tomato-allergic patients, Molecular Nutrition and Food Research

IgE to novel citrus seed allergens among cashew allergic children, Pediatric Allergy and Immunology

Eyelid edema as a predictive factor for sensitization to Pru p 7 in peach allergy, The Journal of Dermatology

Does atopic dermatitis cause food allergy? A systematic review, The Journal of Allergy and Clinical Immunology

Enquiring About Tolerance (EAT) study: Feasibility of an early allergenic food introduction regimen, The Journal of Allergy and Clinical Immunology

Does Order of Application of Emollient and Topical Corticosteroids Make a Difference in the Severity of Atopic Eczema in Children?  Pediatric Dermatology

Full Articles/Papers

Randomised controlled trial of silk therapeutic clothing for the long-term management of eczema in children, UK Dermatology, Clinical Trials Network

Case Study: Anaphylactic Shock due to Mushroom Soup, Journal of Emergency Medicine Case Reports

Do we need to worry about eating wheat? Nutrition Bulletin


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January – Articles of Interest

Abstract Only

Risk of Asthma from Cesarean Delivery Depends on Membrane Rupture, The Journal of Pediatrics, January 2016

Tolerance of a high-protein baked-egg product in egg-allergic children, Annals of Asthma, Allergy and Immunology, January 2016

Association between chronic urticaria and self-reported penicillin allergy, Annals of Asthma, Allergy and Immunology, January 2016

Hymenoptera Allergy and Mast Cell Activation Syndromes, Current Allergy and Asthma Reports, January 2016

Full Articles

Scurvy in the present times: vitamin c allergy leading to strict fast food diet, Dermatology Online Journal, January 2016 

“You’re Totally on Your Own”: Experiences of Food Allergy on a Canadian University Campus, Universal Journal of Public Health, January 2016

Prime and boost aerosol exposure via fog machine or shisha smoke followed by cinnamon hypersensitivity and anaphylaxis to spiced food, World Allergy Organization Journal, December 2015

A 65-year-old woman with ten-year diarrhea after eating cooked rice, Biomedical Research, January 2016

Debates in allergy medicine: baked egg and milk do not accelerate tolerance to egg and milk, World Allergy Organization Journal, January 2016

Dysphagia in Pediatrics, Children’s Healthcare of Atlanta, November 2015

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Unusual Allergies – Poultry

Allergy to Poultry is well documented and has been known to cause anaphylaxis and airbourne reactions.  The main protein thought to be responsible is Chicken serum albumin (which is identical to alpha livetin found in egg yolk).

This is a partially heat-labile allergen (partially damaged by heat); Small studies have shown that IgE reactivity to Chicken albumin was reduced by 88% after heating at 90 degrees Celsius for 30 minutes.

There is some anecdotal evidence of those unable to eat cooked fresh chicken, but being able to eat chicken which has been fully frozen before being thawed, cooked and eaten. This can be explained by a protein shape change caused by freezing or by cooking for an extended period, essentially damaging the protein so it cannot cause a reaction.

The alpha livetin protein is partially heat labile, so some sufferers will only get reactions from raw chicken and others may get reactions depending on how high a temperature the meat was cooked at and how long for.

Airbourne Reactions

Again, from the Facebook Allergy Groups there is anecdotal evidence of poultry causing eyes to swell closed from handling raw and cooked poultry, so this is a concern and should be avoided if your reaction is this severe. This is of particular concern for people who have allergic asthma or respond to certain allergens with breathing problems.

Potential Cross-Reactivity

In Chicken-allergic patients there have been reports of cross reactions from Parrot, Budgerigar, Chicken, Pigeon, Goose and Duck.

Other members of this group of birds include wildfowl such as pheasants and partridges and commonly eaten birds such as quail and turkey.


Are chicken and egg allergy linked?

This is not an entirely crazy question as one comes from the other. This is sometimes called Bird-Egg Syndrome.

Bird-Egg Syndrome is well studied; it is described as a patient with a poultry allergy who becomes sensitised to birds eggs.

This new sensitivity to egg is to the proteins in egg yolk, alpha livetin (gal d 5), which is found in both chickens and eggs.

Commonly, IgE allergy to egg is usually from the egg white (proteins gal d 1 to 4), so whilst people who are allergic to chickens can become intolerant or allergic to egg, it doesn’t usually work the other way around due to the different proteins involved.

What about feathers?

Inhalable feather dust contains several allergenic components, which cross-react with serum allergens and with similar bird species.

Allergy to bird feathers is not as common as thought in commercial products, after intense production, washing and drying at high temperatures most of the allergenic proteins are removed.

Unprocessed feathers and exposure to the living birds may contain allergens to bird serum proteins (which can cause problems in those allergic to ingesting poultry), bird faeces and feather mites.

Studies have shown that people with egg allergies are unlikely to be allergic to feathers due to the different proteins involved. 

Diagnosis and Management

Diagnosis for poultry allergy can be diagnosed through skin prick tests and IgE blood tests.

As with most allergies symptoms can be managed by avoidance of the offending food or bird by-product.

If you think you suffer from any of these allergies you should seek medical advice from your GP, allergist or dietician

References and Further Reading

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December – Articles of Interest

Full Articles

Different co-sensitizations could determine different risk assessment in peach allergy? Evaluation of an anaphylactic biomarker in Pru p 3 positive patients, Clinical and Molecular Allergy, December 2015

Allergy associations with the adult fecal microbiota: Analysis of the American Gut Project, E Bio Medicine, November 2015

Sensitization pattern to inhalant and food allergens in symptomatic children at first evaluation, Italian Journal of Pediatrics, December 2015

A Qualitative Study of Mothers’ Perceptions of Weaning and the Use of Commercial Infant Food in the United Kingdom, Maternal and Pediatric Nutrition Journal, December 2015

Abstracts Only

Live attenuated influenza vaccine for children with egg allergy, British Medical Journal, December 2015

Clinical and immunological characteristics of a pediatric population with food protein-induced enterocolitis syndrome (FPIES) to fish, Pediatric Allergy and Immunology, December 2015

Interpreting IgE sensitization tests in food allergy, Expert Review of Clinical Immunology, December 2015

Probiotics for allergy prevention, Beneficial Microbes, December 2015

Cross-sensitization profiles of edible nuts in a birch-endemic area, European Journal of Allergy and Clinical Immunology, December 2015

Powder milk: a user-friendly and safe product for heated-milk food challenge? Allergy, Asthma & Clinical Immunology, December 2015

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