IgE to novel citrus seed allergens among cashew allergic children, Pediatric Allergy and Immunology
Case Study: Anaphylactic Shock due to Mushroom Soup, Journal of Emergency Medicine Case Reports
Do we need to worry about eating wheat? Nutrition Bulletin
Dysphagia in Pediatrics, Children’s Healthcare of Atlanta, November 2015
Allergy to Poultry is well documented and has been known to cause anaphylaxis and airbourne reactions. The main protein thought to be responsible is Chicken serum albumin (which is identical to alpha livetin found in egg yolk).
This is a partially heat-labile allergen (partially damaged by heat); Small studies have shown that IgE reactivity to Chicken albumin was reduced by 88% after heating at 90 degrees Celsius for 30 minutes.
There is some anecdotal evidence of those unable to eat cooked fresh chicken, but being able to eat chicken which has been fully frozen before being thawed, cooked and eaten. This can be explained by a protein shape change caused by freezing or by cooking for an extended period, essentially damaging the protein so it cannot cause a reaction.
Read More (re-directed to new site)
End of the month already!
Allergic Reactions to Pine Nut: A Review, J Investig Allergol Clin Immunol, 2015
Lots of great stuff this month
Tolerability to dogfish in children with fish allergy, Allergologia et Immunopathologia
Adverse food reactions from consuming wine, Australian Journal of Grape and Wine Research
Allergic rhinitis: the “Ghost Diagnosis” in patients with asthma, Asthma Research and Practice
EASI does it: a comparison of four eczema severity scales, British Journal of Dermatology
Exercise Induced Anaphylaxis (EIA) is a condition in which moderate to extreme exercise causes anaphylaxis in the patient (and in extreme cases even mild exercise cause symptoms). Many of these cases are further described as Food-Dependent Exercise Induced Anaphylaxis (FD-EIA), where a patient has eaten an allergen and then exercised, causing symptoms.
Symptoms of EIA may start at any stage of exercise or just after it, but in most patients, they begin within 30 min after initiating exercise. The condition has been described in some studies occurring up to 4 hours later.
In comparison FD–EIA, ingestion of the causative food usually precedes exercise by several minutes or even hours. There are some cases where FD–EIA may also occur if the food is ingested soon after the completion of exercise. The triggering factor is important, so that the condition can be properly managed.
Animal allergy, dust mite allergy, pollens and certain drugs have also been known to be part of the trigger for this form of anaphylaxis.
This is a condition within FD-EIA which is well studied as it has been suggested in some studies that over 50% of FD-EIA cases are triggered by wheat allergens (see reference section).
In many cases a weakly positive skin prick for the causative allergen is found. Patients can consume the allergen safely as long as they are not exercising or exercise without eating the allergen and remain safe, it is only the combination which causes anaphylaxis.
Hypothesis for why this happens include:
For FD-EIA, diagnosis can start with skin prick tests (or blood tests) for possible allergens. The result may only be a mild positive.
WD-EIA can be diagnosed the same way, but with IgE for omega-5-gliadin (the major wheat allergen) specifically tested for.
Antihistamines should never be used as an alternative to epipens for those suffering from anaphylaxis. It is recommended in the UK that in these cases that two epipens are prescribed in case of unit failure or a biphasic reaction.
Avoidance of exercise after your trigger allergen is consumed or avoidance of your trigger allergens if you intend to exercise. Management of the condition varies from case to case depending on the severity, but should be discussed with your healthcare provider.
A higher chance of EIA has been linked to:
Knowing which allergens bring the condition on, plus any of the additional factors as above, can all help managing the condition.
Exercise Induced Anaphylaxis should not be confused with cholinergic urticaria, which is chronic hives, which starts with an elevated body temperature.
**I usually use free photos from morguefile for my blog, but this is my football loving daughter practising her kangaroo**
Exercise-Induced Anaphylaxis, Immunology and Allergy Clinics of North America, 2015
Exercise Induced Anaphylaxis, 2013
Exercise-induced anaphylaxis: A clinical view, Italian Journal of Pediatrics, 2012
September already! These are some of the articles I read last month, hope you find them interesting too.
Probiotics for eczema, brands and side-effects, Eczema Life, August 2015
An overview of spectrum of gluten-related disorders, August 2015
Last week we were down in Devon and had the pleasure of visiting Quince Honey Farm in Devon, which is a strange combination of honey museum, live bee hive exhibits (which were my favourite) and a soft play centre for the children (which is the main reason we paid a visit).
I have a friend who is allergic to honey (and bee venom) and a work colleague keeps bees, so this type of allergy has really piqued my interest this week.
Allergy to honey is relatively uncommon, but has been known to cause anaphylaxis. It is thought that the cause of the allergic reaction is either from remnants of the bee in the honey or from minute traces of pollen.
Itch, swell, ooze and wheeze 